In this article we will discuss about the control of reactive ability of tissues by the genotype. While the initial step in the differentiation of cells is made by the cytoplasm, it can be shown that the final result cannot be achieved without the involvement of hereditary factors, the nuclear genes. This is true in particular in the case of [...]
In this article we will discuss about:- 1. The Problem of Reversibility of Differentiation 2. Chemical Substances as Means of Controlling Differentiation 3. Epithelial-Mesenchymal Interactions. The Problem of Reversibility of Differentiation: Differentiation may be reversible to a certain extent. The morphological and physiological peculiarities of tissues require for their maintenance the environment which surrounds them in the normal organism. Except [...]
In experiments of disaggregation and re-aggregation of embryonic cells, there sometimes arise complexes in which differently differentiated tissues are present in chaotic arrangement, having no relation, or only a slight relation, to the arrangement of the same tissues in a normal individual. We have referred to such complexes as teratomas (Fig. 454). The term "teratoma," however, was originally coined to [...]